Publications

Bangert C, Villazala-Merino S, Fahrenberger M, Krausgruber T, Bauer WM, Stanek V, Campion NJ, Bartosik T, Quint T, Regelsberger G, Niederberger-Leppin V, Bock C, Schneider S, Eckl-Dorna J. Comprehensive Analysis of Nasal Polyps Reveals a More Pronounced Type 2 Transcriptomic Profile of Epithelial Cells and Mast Cells in Aspirin-Exacerbated Respiratory Disease. Front Immunol. 2022 Mar 28;13:850494. doi: 10.3389/fimmu.2022.850494. PMID: 35418991; PMCID: PMC8996080.

Colomar-Carando N, Gauthier L, Merli P, Loiacono F, Canevali P, Falco M, Galaverna F, Rossi B, Bosco F, Caratini M, Mingari MC, Locatelli F, Vivier E, Meazza R, Pende D. Exploiting Natural Killer Cell Engagers to Control Pediatric B-cell Precursor Acute Lymphoblastic Leukemia. Cancer Immunol Res. 2022 Mar 1;10(3):291-302. doi: 10.1158/2326-6066.CIR-21-0843. PMID: 35078821.

Croft CA, Thaller A, Marie S, Doisne JM, Surace L, Yang R, Puel A, Bustamante J, Casanova JL, Di Santo JP. Notch, RORC and IL-23 signals cooperate to promote multi-lineage human innate lymphoid cell differentiation. Nat Commun. 2022 Jul 27;13(1):4344. doi: 10.1038/s41467-022-32089-3. PMID: 35896601; PMCID: PMC9329340.

Evren E, Ringqvist E, Doisne JM, Thaller A, Sleiers N, Flavell RA, Di Santo JP, Willinger T. CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages. J Exp Med. 2022 Feb 7;219(2):e20210987. doi: 10.1084/jem.20210987. Epub 2022 Jan 12. PMID: 35019940; PMCID: PMC8759608.

Falco M, Meazza R, Alicata C, Canevali P, Muntasell A, Bottino C, Moretta L, Pende D, Lopez-Botet M. Epitope characterization of a monoclonal antibody that selectively recognizes KIR2DL1 allotypes. HLA. 2022 Aug;100(2):107-118. doi: 10.1111/tan.14630. Epub 2022 Jun 9. PMID: 35411634; PMCID: PMC9544867.

Garcés-Lázaro I, Kotzur R, Cerwenka A, Mandelboim O. NK Cells Under Hypoxia: The Two Faces of Vascularization in Tumor and Pregnancy. Frontiers in Immunology. Front Immunol. 2022 Jun 13;13:924775. doi: 10.3389/fimmu.2022.924775. eCollection 2022.

Haroun-Izquierdo A, Vincenti M, Netskar H, van Ooijen H, Zhang B, Bendzick L, Kanaya M, Momayyezi P, Li S, Wiiger MT, Hoel HJ, Krokeide SZ, Kremer V, Tjonnfjord G, Berggren S, Wikström K, Blomberg P, Alici E, Felices M, Önfelt B, Höglund P, Valamehr B, Ljunggren HG, Björklund A, Hammer Q, Kveberg L, Cichocki F, Miller JS, Malmberg KJ, Sohlberg E. Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia. J Immunother Cancer. 2022 Nov;10(11):e005577. doi: 10.1136/jitc-2022-005577. Erratum in: J Immunother Cancer. 2023 Jan;11(1): PMID: 36319065; PMCID: PMC9628692.

Kotzur R, Duev-Cohen A, Kol I, Reches A, Mandelboim O, Stein N. NK-92 cells retain vitality and functionality when grown in standard cell culture conditions. PLoS One. 2022 Mar 16;17(3):e0264897. doi: 10.1371/journal.pone.0264897. PMID: 35294457; PMCID: PMC8926178.

Meazza R, Falco M, Canevali P, Loiacono F, Colomar-Carando N, Muntasell A, Rea A, Mingari MC, Locatelli F, Moretta L, Lopez-Botet M, Pende D. Characterization of KIR+ NK cell subsets with a monoclonal antibody selectively recognizing KIR2DL1 and blocking the specific interaction with HLA-C. HLA. 2022 Aug;100(2):119-132. doi: 10.1111/tan.14640. Epub 2022 May 15. PMID: 35439359; PMCID: PMC9543057.

Momayyezi P, Malmberg KJ, Hammer Q. Small Interfering RNA Delivery Into Primary Human Natural Killer Cells for Functional Gene Analyses. Curr Protoc. 2022 Nov;2(11):e613. doi: 10.1002/cpz1.613. PMID: 36440989.

Palacios D, Momayyezi P, Huhn O, Ask EH, Dunst J, Malmberg KJ, Hammer Q. An optimized platform for efficient siRNA delivery into human NK cells. Eur J Immunol. 2022 Jul;52(7):1190-1193. doi: 10.1002/eji.202149710. Epub 2022 Apr 22. PMID: 35416292; PMCID: PMC9541389.

Siegler JJ, Correia MP, Hofman T, Prager I, Birgin E, Rahbari NN, Watzl C, Stojanovic A, Cerwenka A. Human ILC3 Exert TRAIL-Mediated Cytotoxicity Towards Cancer Cells. Front Immunol. 2022 Mar 1;13:742571. doi: 10.3389/fimmu.2022.742571. PMID: 35300331; PMCID: PMC8921484.

Wieboldt R, Läubli H. Glycosaminoglycans in cancer therapy. Am J Physiol Cell Physiol. 2022 Jun 1;322(6):C1187-C1200. doi: 10.1152/ajpcell.00063.2022. Epub 2022 Apr 6. PMID: 35385322.

 

Cabo M, Santana-Hernández S, Costa-Garcia M, Rea A, Lozano-Rodríguez R, Ataya M, Balaguer F, Juan M, Ochoa MC, Menéndez S, Comerma L, Rovira A, Berraondo P, Albanell J, Melero I, López-Botet M, Muntasell A. CD137 Costimulation Counteracts TGFβ Inhibition of NK-cell Antitumor Function. Cancer Immunol Res. 2021 Dec;9(12):1476-1490. doi: 10.1158/2326-6066.CIR-21-0030. Epub 2021 Sep 27. PMID: 34580116.

Correia MP, Stojanovic A, Wels WS, Cerwenka A. Innate-like NKp30+CD8+ T cells armed with TCR/CAR target tumor heterogeneity. Oncoimmunology. 2021 Oct 19;10(1):1973783. doi: 10.1080/2162402X.2021.1973783. PMID: 35036073; PMCID: PMC8758178.

Landerer H, Arnone M, Wieboldt R, Goersch E, Stanger AMP, Konantz M, Lengerke C. Two Flow Cytometric Approaches of NKG2D Ligand Surface Detection to Distinguish Stem Cells from Bulk Subpopulations in Acute Myeloid Leukemia. J Vis Exp. 2021 Feb 21;(168). doi: 10.3791/61803. PMID: 33682851.

Quatrini L, Della Chiesa M, Sivori S, Mingari MC, Pende D, Moretta L. Human NK cells, their receptors and function. Eur J Immunol. 2021 Jul;51(7):1566-1579. doi: 10.1002/eji.202049028. Epub 2021 May 10. PMID: 33899224; PMCID: PMC9292411.

Sivori S, Pende D, Quatrini L, Pietra G, Della Chiesa M, Vacca P, Tumino N, Moretta F, Mingari MC, Locatelli F, Moretta L. NK cells and ILCs in tumor immunotherapy. Mol Aspects Med. 2021 Aug;80:100870. doi: 10.1016/j.mam.2020.100870. Epub 2020 Aug 13. PMID: 32800530.

Surace L, Doisne JM, Croft CA, Thaller A, Escoll P, Marie S, Petrosemoli N, Guillemot V, Dardalhon V, Topazio D, Cama A, Buchrieser C, Taylor N, Amit I, Musumeci O, Di Santo JP. Dichotomous metabolic networks govern human ILC2 proliferation and function. Nat Immunol. 2021 Nov;22(11):1367-1374. doi: 10.1038/s41590-021-01043-8. Epub 2021 Oct 22. PMID: 34686862; PMCID: PMC8553616.

Surace L, Doisne JM, Escoll P, Marie S, Dardalhon V, Croft C, Thaller A, Topazio D, Sparaneo A, Cama A, Musumeci O, d'Ecclesia A, Buchrieser C, Taylor N, Di Santo JP. Polarized mitochondria as guardians of NK cell fitness. Blood Adv. 2021 Jan 12;5(1):26-38. doi: 10.1182/bloodadvances.2020003458. PMID: 33570622; PMCID: PMC7805327.

Tschan-Plessl A, Kalberer CP, Wieboldt R, Stern M, Siegler U, Wodnar-Filipowicz A, Gerull S, Halter J, Heim D, Tichelli A, Tsakiris DA, Malmberg KJ, Passweg JR, Bottos A. Cellular immunotherapy with multiple infusions of in vitro-expanded haploidentical natural killer cells after autologous transplantation for patients with plasma cell myeloma. Cytotherapy. 2021 Apr;23(4):329-338. doi: 10.1016/j.jcyt.2020.09.009. Epub 2020 Nov 29. PMID: 33268029. 

 

Chauhan SKS, Koehl U, Kloess S. Harnessing NK Cell Checkpoint-Modulating Immunotherapies. Cancers (Basel). 2020 Jul 6;12(7):1807. doi: 10.3390/cancers12071807. PMID: 32640575; PMCID: PMC7408278.

Mantesso S, Geerts D, Spanholtz J, Kučerová L. Genetic Engineering of Natural Killer Cells for Enhanced Antitumor Function. Front Immunol. 2020 Dec 16;11:607131. doi: 10.3389/fimmu.2020.607131. PMID: 33391277; PMCID: PMC7772419.

Meazza R, Falco M, Loiacono F, Canevali P, Della Chiesa M, Bertaina A, Pagliara D, Merli P, Indio V, Galaverna F, Algeri M, Moretta F, Colomar-Carando N, Muccio L, Sivori S, Pession A, Mingari MC, Moretta L, Moretta A, Locatelli F, Pende D. Phenotypic and Functional Characterization of NK Cells in αβT-Cell and B-Cell Depleted Haplo-HSCT to Cure Pediatric Patients with Acute Leukemia. Cancers (Basel). 2020 Aug 5;12(8):2187. doi: 10.3390/cancers12082187. PMID: 32764469; PMCID: PMC7463940.

Ni J, Wang X, Stojanovic A, Zhang Q, Wincher M, Bühler L, Arnold A, Correia MP, Winkler M, Koch PS, Sexl V, Höfer T, Cerwenka A. Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity. Immunity. 2020 Jun 16;52(6):1075-1087.e8. doi: 10.1016/j.immuni.2020.05.001. Epub 2020 May 22. PMID: 32445619.

Sivori S, Della Chiesa M, Carlomagno S, Quatrini L, Munari E, Vacca P, Tumino N, Mariotti FR, Mingari MC, Pende D, Moretta L. Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer. Front Immunol. 2020 Sep 3;11:2156. doi: 10.3389/fimmu.2020.02156. PMID: 33013909; PMCID: PMC7494755.

 

Kloess S, Kretschmer A, Stahl L, Fricke S, Koehl U. CAR-Expressing Natural Killer Cells for Cancer Retargeting. Transfus Med Hemother. 2019 Feb;46(1):4-13. doi: 10.1159/000495771. Epub 2019 Feb 5. PMID: 31244577; PMCID: PMC6558329.

Sivori S, Meazza R, Quintarelli C, Carlomagno S, Della Chiesa M, Falco M, Moretta L, Locatelli F, Pende D. NK Cell-Based Immunotherapy for Hematological Malignancies. J Clin Med. 2019 Oct 16;8(10):1702. doi: 10.3390/jcm8101702. PMID: 31623224; PMCID: PMC6832127.